Treating fatty liver disease by modulating mitochondrial pyruvate metabolism
نویسندگان
چکیده
Modifying the entry of pyruvate into mitochondria may provide a unique approach to treat metabolic disease. The pharmacology of a new class of insulin sensitizers directed against a newly identified mitochondrial target may treat many aspects of nonalcoholic steatohepatitis, including fibrosis. This commentary suggests treating nonalcoholic steatohepatitis through a newly identified mechanism consistent with pathophysiology. (Hepatology Communications 2017;1:193-197).
منابع مشابه
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2017